WA
Job Description
- Perform Polymorph screening as per guideline
- Follow cGMP Documentation and EHS compliance at workplace
- Perform Virtual and Experimental Screen and evaluate all literature that relates to solid-state issues
- Screen new forms by performing stress tests and File ASAP new forms in patent application
- Analyze laboratory samples by XRD, DSC, TGA and other characterization techniques
- Assess kinetic stability and interconversions and produce scheme of all polymorphic transitions
- Produce solubility curves of different polymorphs and assess thermodynamic stability relationships
- Develop detection methods to assess polymorphic purity and monitor in the laboratory samples
- Support the development of the crystallization process with full characterization
- Monitoring stability and physical properties of micronized/milled materials
- Perform calibration, method development, method validation, and troubleshooting using various instruments like PXRD, DSC, TGA and Particle size analyzer
- Knowledge of various regulatory guidelines w.r.t. method development, product development, and documentation